The gonadal steroids, estradiol, testosterone and progesterone, alter neuroendocrine function and behavior in adult mammals and do so by acting on the central nervous system and pituitary gland. Besides intracellular receptor sites, various cellular and chemical actions of gonadal steroids are being studied within the brain and pituitary. The review summarizes the present state of such research and points as well to new advances in our understanding of the cellular basis of developmental events such as brain sexual differentiation and puberty, which are influenced by gonadal steroids.
Drugs can be added and removed from this list by WADA annually, although not all of the banned substances are explicitly named. Caroline Hatton, PhD , a sports anti-doping science consultant, told in a Mar. 12, 2010 email that "A key concept in prohibited lists is that they avoid being finite. Instead of listing all banned drugs one by one, they list entire drug classes and name drugs merely as examples. This is to keep users who took designer drugs from claiming that they didn't break the rules because the drugs they took weren't listed."