-Initial dose: 5 mcg subcutaneously twice a day for at least 1 month
-Maintenance dose: Based on clinical response, may increase to 10 mcg subcutaneously twice a day
-Maximum dose: 10 mcg twice a day
-Administer within the 60-minute period before the morning and evening meals; alternatively, may give before the two main meals of the day provided dosing is 6 hours or more apart; do not administer after a meal.
-Patients may switch from immediate-release Byetta to extended-release Bydureon, although prior treatment with the immediate-release injection is not necessary.
-For patients who do switch, discontinue immediate-release Byetta on initiation of extended-release Bydureon; transient elevations in blood glucose may occur and generally improve within the first 2 weeks of initiation.
-For patients concomitantly receiving a sulfonylurea, a lower dose of the sulfonylurea may be required to reduce the risk of hypoglycemia.
Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus