Prescription nasal spray with steroids

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In a pharmacokinetic study in 30 healthy adult subjects, the relative bioavailability ( BA ) of one nasal spray in one nostril (4 mg total dose, mL of 40 mg/mL naloxone hydrochloride solution) and two nasal sprays administered as one nasal spray in each nostril (8 mg total dose, mL of 40 mg/mL naloxone hydrochloride solution in each nostril) was compared to a single dose of mg naloxone hydrochloride intramuscular injection. For intranasal administration, the subjects were instructed not to breathe through the nose during administration of the nasal spray, and remained fully supine for approximately one hour post-dose. For intramuscular administration, naloxone was administered as a single injection in the gluteus maximus muscle. The pharmacokinetic parameters obtained in the study are shown in Table 1.

Prescription nasal spray with steroids

prescription nasal spray with steroids

In a pharmacokinetic study in 30 healthy adult subjects, the relative bioavailability ( BA ) of one nasal spray in one nostril (4 mg total dose, mL of 40 mg/mL naloxone hydrochloride solution) and two nasal sprays administered as one nasal spray in each nostril (8 mg total dose, mL of 40 mg/mL naloxone hydrochloride solution in each nostril) was compared to a single dose of mg naloxone hydrochloride intramuscular injection. For intranasal administration, the subjects were instructed not to breathe through the nose during administration of the nasal spray, and remained fully supine for approximately one hour post-dose. For intramuscular administration, naloxone was administered as a single injection in the gluteus maximus muscle. The pharmacokinetic parameters obtained in the study are shown in Table 1.

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