What is it? An anabolic/androgenic steroid altered to produce better muscle-building properties, making it very popular for bodybuilders.
How it’s taken: Tablets or injections
Brand names: Winstrol, although that brand is no longer in production in the United States.
Legalities: Regulated as a Schedule III drug, meaning a valid prescription is required for possession.
What it does: Promotes muscle growth. In the past, it has been prescribed for patients with osteoporosis, growth deficiencies and hereditary angioedema, a disease that causes swelling.
Side effects/risks: Oily skin, acne and hair loss. More severe risks include liver damage, cardiovascular strain, mood changes and hardening of the arteries.
In the news: Canadian sprinter Ben Johnson was stripped of his 1988 Olympic gold medal after testing positive for stanozolol.
“How About No” was defined on Urban Dictionary  in 2005. In April 2008, an image macro with the phrase appearing as a caption on a photo of Dr. Evil was added to Threadbombing.  Three years later, it was also added to reaction photo repository My Face When.  In November 2011, the Facebook fan page “How About NO?”  was created, gaining more than 1,500 likes as of June 2013. At least two images titled “How About No” have appeared on the front page of Reddit including a photo of a dog submitted to /r/Funny  in May 2012 and a sloth GIF (shown below) submitted to /r/sloths in March 2013. Also that March, The Chive  posted a compilation of 25 photos that evoked the sentiment of the phrase. “How About No” is also a popular hashtag on Tumblr  , Twitter  and Instagram  , where more than 19,000 photos have been tagged #howaboutno.