Steroid induced diabetes in pregnancy

Diagnosis Index entries containing back-references to :

  • Diabetes, diabetic (mellitus) (sugar) ICD-10-CM Diagnosis Code Type 2 diabetes mellitus without complications
      2016 2017 2018 Billable/Specific Code Questionable As Admission Dx
    • with
      • retinopathy ICD-10-CM Diagnosis Code Type 2 diabetes mellitus with unspecified diabetic retinopathy without macular edema
          2016 2017 2018 Billable/Specific Code
        • with macular edema
    • type 2 ICD-10-CM Diagnosis Code Type 2 diabetes mellitus without complications
        2016 2017 2018 Billable/Specific Code Questionable As Admission Dx
      • with
        • retinopathy ICD-10-CM Diagnosis Code Type 2 diabetes mellitus with unspecified diabetic retinopathy without macular edema
            2016 2017 2018 Billable/Specific Code
          • with macular edema

Cells of the zona fasciculata and zona reticularis lack aldosterone synthase (CYP11B2) that converts corticosterone to aldosterone, and thus these tissues produce only the weak mineralocorticoid corticosterone. However, both these zones do contain the CYP17A1 missing in zona glomerulosa and thus produce the major glucocorticoid, cortisol. Zona fasciculata and zona reticularis cells also contain CYP17A1, whose 17,20-lyase activity is responsible for producing the androgens, dehydroepiandrosterone (DHEA) and androstenedione. Thus, fasciculata and reticularis cells can make corticosteroids and the adrenal androgens, but not aldosterone.

Treatment: If a pancreatic or liver tumor is identified and able to be surgically excised, the skin lesions may normalize for an extended period of time, but because these tumors metastasize (spread to other areas of the body) quickly, surgery is not curative. In cases of end stage liver disease, surgery is not possible, and the goal of therapy is to increase quality of life and decrease uncomfortable skin lesions with supportive care and addressing the nutritional abnormalities. Supportive care includes supplementing protein and necessary minerals and enzymes through the diet and oral supplements or by weekly intravenous amino acid infusions that are performed in the hospital on an outpatient basis until improvement in the skin is noted. Unfortunately, despite the supportive care, the disease will progress.

Steroid induced diabetes in pregnancy

steroid induced diabetes in pregnancy

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