Steroidal aromatase inhibitor side effects

BRCA2 gene is located on chromosome 13q12 and also classified as a tumour suppressor gene; though shares no homology with the BRCA1 gene. However, it can bind with BRCA1 to participate in DNA damage response pathway. BRCA2 protein functions as a mediator of the core mechanism of homologous recombination. Its mutations are linked to breast carcinomas that are ER and PR positive.  Though rarely associated with basal-like phenotype but still linked to a higher grade (II or III) when compared to age-matched sporadic cases

Then we’re left with PCT Clomid use. Standard PCT Clomid doses will normally start at 100-150mg per day for 1-2 weeks. From here the dose will drop to 50-100mg per day for 1-2 weeks and finish with 1-2 weeks at 50mg per day. Total Clomid therapy should last 4-6 weeks, so dosing should be based and considered on that total schedule. Most will also be far more successful in their PCT recovery by including Nolvadex and HCG. Timing is also important when planning your Clomid PCT use, and this timing factor will vary depending on the inclusion of HCG:

Research suggests the common table mushroom has anti- aromatase [17] properties and therefore possible anti-estrogen activity. In 2009, a case-control study of the eating habits of 2,018 women in southeast China revealed that women who consumed greater than 10 grams of fresh mushrooms or greater than 4 grams of dried mushrooms per day had an approximately 50% lower incidence of breast cancer. Chinese women who consumed mushrooms and green tea had a 90% lower incidence of breast cancer. [18] However the study was relatively small (2,018 patients participating) and limited to Chinese women of southeast China.

Steroidal aromatase inhibitor side effects

steroidal aromatase inhibitor side effects

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