My foot & ankle specialist prescribed a compounded transdermal cream for nerve pain along the outside of my foot right below the ankle from toes to heels & it helps. I’m also been using it for fibromyalgia pain. I recently tried it for varicose vein pain & have found it works for that too. Very pleased with results. I am diabetic so it also greatly helps with diabetic nerve pain in the feet. Very easy to use, mine comes in a clear plastic container that dispenses the right amount for each dose much like a lotion pump. Just need to rub it in well. No mess, no pill. I think a physician has to place the order with the pharmacy.